Epithelan
For laboratory and research purposes only. Not for human consumption, veterinary use, or medical applications.
What is Epithelan?
Epithelan is a peptide complex researched for its potential role in epithelial cell regeneration and telomere maintenance. Studies suggest this peptide may influence cellular aging processes and epithelial tissue repair. Research applications include dermatological studies, wound healing research, and cellular longevity investigations.
How Does Epithelan Work?
Epithelan is thought to act by stimulating telomerase activity in somatic cells, thereby elongating telomeres and extending the replicative lifespan of epithelial cells. It also modulates the hypothalamic-pituitary axis and has been shown to normalize melatonin secretion from the pineal gland in aged subjects in animal studies. Additionally, Epithelan appears to regulate gene expression through epigenetic mechanisms, reducing oxidative DNA damage markers and inflammatory cytokine output.
Research Applications
- Telomere maintenance and cellular aging studies
- Epithelial cell regeneration research
- Antioxidant and oxidative stress models
- Neuroendocrine regulation investigations
- Longevity and anti-aging pathway research
Specifications
Storage & Handling
Store lyophilized peptide at -20°C protected from light. Once reconstituted, store at 4°C for up to 2 weeks or at -20°C for up to 3 months. Avoid repeated freeze-thaw cycles. Recommended reconstitution solvent: sterile water.
For laboratory and research purposes only. Not for human consumption, veterinary use, or medical applications.
Scientific References
- Khavinson VK, et al. Epitalon peptide induces telomerase activity and telomere elongation in human somatic cells. Bull Exp Biol Med. 2003;135(6):590-2.
- Anisimov VN, et al. Effect of Epitalon on biomarkers of aging, life span and spontaneous tumor incidence in female Swiss-derived SHR mice. Biogerontology. 2003;4(4):193-202.
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