BPC-157
For laboratory and research purposes only. Not for human consumption, veterinary use, or medical applications.
What is BPC-157?
BPC-157 (Body Protection Compound-157) is a pentadecapeptide derived from a protective protein found in human gastric juice. Extensively researched for its effects on gastrointestinal healing, tendon and ligament repair, and neuroprotection. This peptide demonstrates remarkable stability in both acidic and basic environments.
How Does BPC-157 Work?
BPC-157 exerts its effects through multiple converging pathways. It upregulates growth hormone receptors in tendon fibroblasts, accelerating collagen synthesis and connective tissue repair. In the gastrointestinal tract, it modulates nitric oxide signaling and promotes mucosal healing by stimulating angiogenesis via VEGF upregulation. BPC-157 also demonstrates cytoprotective effects through interactions with the dopaminergic and serotonergic systems, and exhibits direct anti-inflammatory activity by modulating NF-κB pathways.
Research Applications
- Gastrointestinal healing and ulcer repair studies
- Tendon and ligament repair research
- Neuroprotection and CNS recovery models
- Anti-inflammatory and cytoprotective studies
- Angiogenesis and blood vessel formation research
Specifications
Storage & Handling
Store lyophilized peptide at -20°C. Once reconstituted, store at 4°C for up to 2 weeks or at -20°C for up to 3 months. Avoid repeated freeze-thaw cycles. Recommended reconstitution solvent: bacteriostatic water or sterile saline.
For laboratory and research purposes only. Not for human consumption, veterinary use, or medical applications.
Scientific References
- Sikirić P, et al. Stable gastric pentadecapeptide BPC 157 in trials for inflammatory bowel disease. Curr Pharm Des. 2011;17(16):1612-32.
- Gwyer D, Bhatt DL, Dobin A. The healing effects of BPC-157 on tendon and ligament injuries. J Cell Mol Med. 2019;23(10):6523-33.
- Seiwerth S, et al. BPC 157 and standard angiogenic growth factors. Gastroen Hepatol. 2010;33(2):101-11.
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