Ipamorelin
For laboratory and research purposes only. Not for human consumption, veterinary use, or medical applications.
What is Ipamorelin?
Ipamorelin is a synthetic pentapeptide that acts as a selective growth hormone secretagogue and ghrelin receptor (GHS-R1a) agonist. It stimulates pulsatile growth hormone release with minimal effect on cortisol, prolactin, or appetite, making it one of the most selective GH secretagogues studied. Research applications include growth hormone secretion studies, body composition research, and recovery investigations.
How Does Ipamorelin Work?
Ipamorelin selectively binds the growth hormone secretagogue receptor (GHS-R1a) on pituitary somatotroph cells, mimicking endogenous ghrelin to trigger pulsatile growth hormone release. Unlike non-selective secretagogues, it stimulates GH without meaningfully elevating cortisol, prolactin, or aldosterone, and without the strong appetite stimulation associated with ghrelin itself. The resulting physiological GH pulse drives hepatic IGF-1 production, which mediates the downstream anabolic and metabolic effects studied in body composition and recovery research.
Research Applications
- Growth hormone secretion and pulsatility studies
- Body composition and lean mass research
- Selective GH release vs. cortisol/prolactin specificity studies
- Bone density and tissue recovery models
- Pituitary somatotroph function investigations
Specifications
Storage & Handling
Store lyophilized peptide at -20°C. Once reconstituted, store at 4°C for up to 1 week or at -20°C for up to 2 months. Avoid repeated freeze-thaw cycles. Recommended reconstitution solvent: sterile water.
For laboratory and research purposes only. Not for human consumption, veterinary use, or medical applications.
Scientific References
- Raun K, et al. Ipamorelin, the first selective growth hormone secretagogue. Eur J Endocrinol. 1998;139(5):552-61.
- Gobburu JV, et al. Pharmacokinetic-pharmacodynamic modeling of ipamorelin, a growth hormone releasing peptide, in human volunteers. Pharm Res. 1999;16(9):1412-6.
Related Products
CJC-1295 (No DAC)
99%+Growth hormone secretagogue without drug affinity complex.
MOTS-c
99%+Mitochondrial-derived peptide for metabolic and longevity research.
TB-500
99%+Thymosin Beta-4 fragment for tissue repair and recovery research.